NatA Complex: A Protein Regulating Gene Expression and DNA Replication

Target Name: N-Terminal Acetyltransferase A (NatA) Complex

NCBI ID: P16627

N-Terminal Acetyltransferase A (NatA) Complex

Other Name(s): NatA Complex | N-alpha-Acetyltransferase | NatA

NatA Complex: A Protein Regulating Gene Expression and DNA Replication

N-Terminal Acetyltransferase A (NatA) Complex is a protein that plays a crucial role in the regulation of gene expression and DNA replication in eukaryotic cells. The NatA complex is composed of multiple proteins that work together to add acetyl groups to specific target DNA sequences. This process is critical for the regulation of gene expression, DNA replication, and other cellular processes.

The NatA complex is a complex protein that is highly conserved across different species, including bacteria, yeast, plants, and animals. It is composed of several subunits, including NatA1, NatA2, NatA3, and NatA4, which work together to add acetyl groups to specific target DNA sequences.

NatA1 is the catalytic subunit of the NatA complex and is responsible for the addition of acetyl groups to specific target DNA sequences. It has a molecular weight of approximately 46 kDa and a pI of approximately 6.5. NatA1 is expressed in a variety of organisms, including bacteria, yeast, plants, and animals, and is involved in the regulation of gene expression and DNA replication.

NatA2 is a regulatory subunit of the NatA complex that is responsible for the regulation of gene expression. It has a molecular weight of approximately 13 kDa and a pI of approximately 9.5. NatA2 is expressed in a variety of organisms, including bacteria, yeast, plants, and animals, and is involved in the regulation of gene expression and DNA replication.

NatA3 is a regulatory subunit of the NatA complex that is responsible for the regulation of gene expression. It has a molecular weight of approximately 13 kDa and a pI of approximately 9.5. NatA3 is expressed in a variety of organisms, including bacteria, yeast, plants, and animals, and is involved in the regulation of gene expression and DNA replication.

NatA4 is a regulatory subunit of the NatA complex that is responsible for the regulation of gene expression. It has a molecular weight of approximately 6.5 kDa and a pI of approximately 6.5. NatA4 is expressed in a variety of organisms, including bacteria, yeast, plants, and animals, and is involved in the regulation of gene expression and DNA replication.

The NatA complex plays a crucial role in the regulation of gene expression and DNA replication in eukaryotic cells. It is composed of multiple subunits that work together to add acetyl groups to specific target DNA sequences. This process is critical for the regulation of gene expression, DNA replication, and other cellular processes.

In recent years, the NatA complex has gained significant attention as a potential drug target or biomarker. The addition of acetyl groups to specific target DNA sequences by the NatA complex is thought to play a role in the regulation of gene expression and may be a potential target for small molecules that can inhibit this process.

For example, studies have shown that inhibitors of the NatA complex have the potential to be effective in treating a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. These inhibitors work by binding to specific regions of the NatA complex and inhibiting its activity.

In addition to its potential as a drug target, the NatA complex has also been identified as a potential biomarker for a variety of diseases. The addition of acetyl groups to specific target DNA sequences by the NatA complex is thought to be a potential diagnostic or prognostic factor for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Overall, the NatA complex is a protein that plays a crucial role in the regulation of gene expression and DNA replication in eukaryotic cells. It is composed of multiple subunits that work together to add acetyl groups to specific target DNA sequences. This process is

Protein Name: N-Terminal Acetyltransferase A (NatA) Complex

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